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He says ulcerative colitis patients often have significant pain from arthritis or joint pain and frequently use anti-inflammatory drugs to treat the painHowevertraditional anti-inflammatory drugslike ibuprofen and naproxenhave been linked to ulcerative colitis flare-upsThis study suggests that Celebrex is a good alternative to other anti-inflammatory drugs.

Ulcerative colitis patients taking Celebrex also seemed to fare better with disease severityWhen researchers examined biopsy specimensthey sawan increase in disease severity in the placebo patientsSandborn says.

Alternative therapies for treatment of JRA should be considered in pediatric patients identified to be CYP2C9 poor metabolizerssee Poor Metabolizers of CYP2C9 substrates

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